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Albumin-Bound Paclitaxel [Taj Pharma] Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat breast cancer, lung cancer and pancreatic cancer, among others. Softaxel (paclitaxel and docetaxel) are highly active chemotherapeutic agents in the treatment of breast cancer. Being hydrophobic, Softaxel require solvents (Cremphor EL or polysorbate) to enable parenteral administration. These solvents contribute to the main toxicities seen with Softaxel (hypersensitivity, peripheral neuropathy, and myelo-suppression). Cremophor EL can also leach plasticizers from polyvinyl chloride tubing, which can result in severe, sometimes fatal, anaphylactic reactions. To prevent or limit the onset of hypersensitivity reactions, corticosteroids and antihistamines are standard premedica-tion with Softaxel. Furthermore, Cremophor EL entraps paclitaxel into circulating micelles, which reduces its availability an...

  Lisinopril is a medicine to treat high blood pressure and heart failure. It's also prescribed after a heart attack and in diabetic kidney disease. Lisinopril helps prevent future strokes and heart attacks. It also improves your survival if you're taking it after a recent heart attack or for heart failure. And it also slows down diabetic kidney disease. This medicine is only available on prescription. It comes as tablets. It also comes as a liquid for people who find it hard to swallow tablets, but this has to be ordered specially by your doctor. Lisinopril is also available combined with another blood pressure medicine called hydrochlorothiazide. NHS coronavirus advice If you have coronavirus, or think you might have it, keep taking your blood pressure medicines as usual. There is no clear evidence that taking angiotensin-converting enzyme (ACE) inhibitors like lisinopril will cause complications. Updated: 17 March 2020 2. Key facts Lisinopril lowers your blood pressure and m...