L Alanyl L Glutamine Injection - By Taj Pharma [एल ग्लूटामिन]

 L Alanyl L Glutamine Injection - By Taj Pharma [एल ग्लूटामिन]

L-alanyl-L-glutamine Uses

L-alanyl-L-glutamine is used in the treatment of Short term fluid replacement after trauma.

How L-alanyl-L-glutamine works

L-alanyl-L-glutamine belongs to class of drugs called amino acids. It works by inhibiting the muscle break down and increases the synthesis of muscle proteins and also it improves electrolyte and water absorption in the intestines and increases the body’s natural defense mechanism.

Common side effects of L-alanyl-L-glutamine

No common side effects seen

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Full Generic Medicine Info
Dosage/Direction for Use

Intravenous
As part of an IV parenteral nutrition regimen
Adult: Dosage is individualised according to severity of the catabolic state and amino acid/protein requirements. In a hypercatabolic state: As 200 mg/mL solution for infusion: 300-500 mg/kg daily. The proportion of the amino acids supplied should not exceed approx 30% of the total amino acid supply. Max: 500 mg L-alanyl-L-glutamine/kg daily; 2,000 mg amino acids/kg daily. Max duration of treatment: 3 weeks.
Contraindications
Severe metabolic acidosis. Severe hepatic and renal impairment (CrCl <25 mL/min).
Special Precautions
Mild to moderate hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor serum electrolytes, osmolarity and bilirubin, water balance, acid-base status and LFTs (e.g. alkaline phosphatase, ALT/AST); signs and symptoms of hyperammonaemia.
Action
L-alanyl-L-glutamine is used as a part of parenteral nutrition. In the body, it endogenously split into two amino acids, alanine and glutamine. The released amino acid flow as nutrients into their respective body pools and are metabolised according to the needs of the organism. Synonym: N(2)-L-alanyl-L-glutamine, alanylglutamine.
Excretion: Elimination half-life: 2.4-3.8 minutes.
Storage
Intravenous: Store below 25°C. Any unused portions should be disposed of in accordance with local requirements.
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